Parizvino, neotame yakabvumidzwa nenyika dzinopfuura zana kuti ishandiswe mumhando dzinopfuura zana dzezvigadzirwa.
Inokodzera kushandiswa mu carbonated soft drinks, yoghurts, makeke, drink powders, bubble gums pakati pezvimwe zvekudya.Inogona kushandiswa setafura yepamusoro inotapira yezvinwiwa zvinopisa sekofi.Inovhara zvinovava .
HuaSweet neotame inoenderana neChinese yenyika chiyero GB29944 uye inonyatso kusangana neFCCVIII, USP, JECFA uye EP zvakatemwa.HuaSweet yakagadzira network yekutengesa munyika dzinopfuura makumi masere muSoutheast Asia, Europe, South America, North America neAfrica.
Muna 2002, FDA yakachitendera sechinhu chisiri chekudya chinovaka muviri uye chinonamisa kunaka mukati meUnited States muchikafu kazhinji, kunze kwenyama nehuku.[3]Muna 2010, yakatenderwa kushandiswa muchikafu mukati meEU ine nhamba yeE961.[5]Yakabvumidzwawo sekuwedzera mune dzimwe nyika dzakawanda kunze kweUS neEU.
MuUS neEU, inogamuchirwa yemazuva ese yekudya (ADI) yeneotame kuvanhu ndeye 0.3 uye 2 mg pakg yehuremu hwemuviri (mg/kg bw), zvichiteerana.NOAEL kuvanhu i200 mg/kg bw pazuva mukati meEU.
Zvinofungidzirwa zvinogoneka zvezuva nezuva kubva mukudya zviri pazasi peADI-mazinga.Neotame yakabatwa inogona kuumba phenylalanine, asi mukushandiswa kwakajairika kweneotame, izvi hazvina kukosha kune avo vane phenylketonuria.Iyo zvakare haina mhedzisiro yakaipa mumhando ye2 chirwere cheshuga.Haisi kuonekwa secarcinogenic kana mutagenic.
Iyo Center for Science muPublic Interest inoisa neotame seyakachengeteka.